HandySPIM - PhotonTech Innovations Co., Ltd.

PhotonTech Innovations Co., Ltd.

Portable Light-sheet source HandySPIM

Turn your microscope into a 3D fluorescence microscope with our low-cost & high resolution light-sheet source HandySPIM.

Participation in Photonics West: Exhibition and Conference Presentation

We will exhibit the HandySPIM light-sheet microscope light source and the LUCID-B tissue-clearing reagent, and also give a related academic presentation at SPIE Photonics West, an international conference to be held at the Moscone Center, San Francisco, USA, in January 2026.

Exhibition: SPIE BiOS Expo (January 17–18, 2026)
Booth No. 8212
https://spie.org/conferences-and-exhibitions/photonics-west/exhibitions/bios-expo

Academic Presentation: 3D imaging of biological specimens using the LUCID clearing reagent and the HandySPIM lens-free light-sheet module (January 19, 2026, 16:35–16:55 Moscone South, Room 302)
https://spie.org/photonics-west/presentation/3D-imaging-of-biological-specimens-using-the-LUCID-clearing-reagent/13855-10

Note: During the SPIE Photonics West Expo (January 20–22, 2026), the HandySPIM light-sheet microscope light source will also be exhibited at the booth of Nippon Electric Glass Co., Ltd. (NEG) (Booth No. 3389).

What's HandySPIM?

HandySPIM is world's only one technology that has following features.

Low price & High resolution
Wide-area shooting in a short time
Handy size & run on a power bank
Virtual scan from low to high magnification
Can be mounted on various upright or stereo microscopes
HE & Immunostaining OK after 3D observation
In combination with LUCID clearing reagent, 3D observation is possible without slicing the specimen (preventing missed lesions)

Also, HandySPIM can be mouted on various upright microscopes or stereo microscopes.

Comparison with conventional selective plane illumination microscopies (SPIM)

HandySPIM observation samples

小見出し

ここをクリックして表示したいテキストを入力してください。テキストは「右寄せ」「中央寄せ」「左寄せ」といった整列方向、「太字」「斜体」「下線」「取り消し線」、「文字サイズ」「文字色」「文字の背景色」など細かく編集することができます。

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Papers & Presentations

Development of lensless light-sheet sources and their application for compact selective plane illumination microscopy (SPIM) (Invited Paper, Paper 13323-36), Photonics West 2025
Realization of 3D observation of transparency-enhanced tissue specimens with a palm-sized device (Press Release, Jan 30, 2025)
ここをクリックして表示したいテキストを入力してください。

How to use HandySPIM

Video in preperation.

Specification

項目・枠線付き(スマホ横スクロール) はタブレット以上のサイズでのみ編集可能です
（実際の公開ページではタブレットサイズ以下で横スクロールが表示されます）

Dimensions (AU2100)	Light Source Unit (excluding height adjustment knob): W 170 mm × D 42 mm × H 28 mm, approx. 335 g Control Panel (excluding LED switches): W 145 mm × D 90 mm × H 30 mm, approx. 265 g
Max observable sample size	Up to 30 mm (width) × 4–5 mm (depth) × 2 mm (height/depth) Please use the dedicated sample containers (included).
Light sources	Violet: 405 nm Blue: 470 nm Yellow: 590 nm
Power input (AU2100)	5V, 3.2A or higher, USB-C Power Delivery supported
Sample stage travel range	AU2100: ±3 mm (max) AU2300: ±4 mm (max)
Standard Accessories (AU2100)	Sample container (well type), Sample container (wide type), Glass unit Replacement sample containers and glass units are available for individual purchase.
見出し	ここをクリックして表示したいテキストを入力してください。テキストは「右寄せ」「中央寄せ」「左寄せ」といった整列方向、「太字」「斜体」「下線」「取り消し線」、「文字サイズ」「文字色」「文字の背景色」など細かく編集することができます。

Sales information

Available in USA.

General sales of HandySPIM began in November 2024.
In addition, sales of the HandySPIM motorized Z-stage model started in summer 2025.

For pricing and delivery time, please contact us.

HandySPIM AU2100　(Two-color light source, manual Z-stage)
You may select two colors from the following light sources:
Violet (405 nm), Blue (470 nm), and Yellow (590 nm).

HandySPIM AU2300　(Two-color light source, motorized Z-stage)
The available light sources are the same as those of the manual Z-stage model.
Using the included PC software, the sample stage can be controlled electronically.

Note: The motorized Z-stage model cannot be powered by a mobile battery.